Chronic lymphocytic thyroiditis and tumor-infiltrating lymphocytes combined in thyroid papillary carcinoma Tiroid papiller karsinomlarinda kronik lenfositik tiroidit ve tümörü infiltre eden lenfosit birlikteliǧi
Turk Onkoloji Dergisi, cilt.24, sa.4, ss.172-176, 2009 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 24 Sayı: 4
- Basım Tarihi: 2009
- Dergi Adı: Turk Onkoloji Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.172-176
- Anahtar Kelimeler: Lymphocytic thyroiditis, Papillary carcinoma, Thyroid, Tumor-infiltrating lymphocytes
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
OBJECTIVES This study examined the frequency of chronic lymphocytic thyroiditis (CLT) in thyroid papillary carcinomas (TPC) and the relationship between the presence of tumor-infiltrating lymphocytes (TIL) and CLT. METHODS The study included 61 TPC cases. In each case, the presence of the lymphocyte infiltration in the tumor tissue and non-neoplastic parenchyma was graded semi-quantitatively using a scale of 0 to 3. The cases were classified in two groups, TPC including CLT (Group I) and TPC not including CLT (Group II). RESULTS CLT was detected in 26.3% (Group I) of the TPCs and TIL was observed in 77% of the Group I cases; no lymphoid infiltration compatible with TIL was detected in Group II. A significant difference was observed in the TIL density between Groups I and II. CONCLUSION CLT is a frequent finding in TPC, and the presence of TIL is related to CLT. © 2009 Association of Oncology.