Vascular occlusion following hyaluronic acid injection: A case report


Özkan R., Kaya B., Kaya G.

Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, cilt.53, sa.1, ss.47-50, 2026 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Sayı: 1
  • Basım Tarihi: 2026
  • Dergi Adı: Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, MEDLINE, Natural Science Collection (ProQuest), Biomedical Reference Collection: Corporate Edition (EBSCO), Earth, Atmospheric, & Aquatic Science Collection (ProQuest), Health Research Premium Collection (ProQuest)
  • Sayfa Sayıları: ss.47-50
  • Anahtar Kelimeler: Filler complications, hyaluronidase hyperbaric oxygen treatment, hyaluronic acid, intra-arterial injection
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Introduction: This case presentation discusses vascular occlusion following hyaluronic acid (HA) injection and the subsequent treatment. Case Report: A 52-year-old female underwent a 0.2 ml HA filler injection for aesthetic purposes in the forehead area, followed by the development of discoloration and severe pain extending from the glabellar region to the forehead. Discussion: The diagnosis was determined as vascular occlusion due to the injection, and the patient received 300 IU of hyaluronidase immediately. Additionally, hyperbaric oxygen treatment (HBO₂) was initiated. The patient received seven HBO₂ treatments and healed without developing post-treatment necrosis. No scar formation was observed at the three-month follow-up. This case highlights the potential benefits of HBO₂ in managing complications arising from HA fillers. It underscores the importance of physicians performing aesthetic procedures, being attentive to facial anatomy and injection techniques to prevent such complications. Furthermore, having knowledge about the effectiveness of HBO₂ in potential complication scenarios and collaboration with hyperbaric clinics when necessary are recommended.