The relationship between systemic inflammation response index and clinical and histopathological features in gastric cancer La relación entre el índice de respuesta a la inflamación sistémica y las características clínicas e hitopatológicas en el cáncer gástrico
Cirugia y Cirujanos, cilt.93, sa.2, ss.158-165, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 93 Sayı: 2
- Basım Tarihi: 2025
- Doi Numarası: 10.24875/ciru.23000234
- Dergi Adı: Cirugia y Cirujanos
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Directory of Open Access Journals
- Sayfa Sayıları: ss.158-165
- Anahtar Kelimeler: Systemic inflammation response index, Gastric adenocancer, Clinical features, Gastric adenocancer, Systemic inflammation response index
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: The systemic inflammation response index (SIRI) is a marker used to predict survival. The aim of this study is to examine the relationship between SIRI and clinicopathological features and survival. Method: The relationship between clinicopathological characteristics and survey and SIRI was retrospectively investigated. Results: A total of 178 patients were included in the study. Poor prognostic factors such as tumor size, t, T-stage, tumor-node-metastasis (TNM) stage, and CA19-9 level were found to have a statistically significant relationship with patients with high SIRI (p = 0.039, p = 0.001, p = 0.001 and p = 0.013, respectively). A high SIRI was found to be an independent and poor prognostic factor for 3-year and 5-year survival (p = 0.014 and p = 0.027, respectively). Conclusions: High SIRI was associated with a poor survival rate, as were advanced TNM stage, advanced T stage, larger tumor size, and elevated CA19-9 level; all these are poor prognostic markers for gastric cancer.