The effect of neutrophil lymphocyte ratio and monocyte HDL ratio in indicating additional arterial disease in patients scheduled to undergo elective coronary bypass operation
Kuwait Medical Journal, cilt.53, sa.4, ss.411-416, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 53 Sayı: 4
- Basım Tarihi: 2021
- Dergi Adı: Kuwait Medical Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
- Sayfa Sayıları: ss.411-416
- Anahtar Kelimeler: carotid artery disease, coronary artery disease, monocyte to HDL ratio, neutrophil to lymphocyte ratio, peripheral artery disease
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: We aimed to investigate the role of neutrophil/ lymphocyte ratio (NLR) and monocyte/ high density lipoprotein ratio (MHR) in routine blood tests before surgery in predicting the presence of carotid artery and peripheral artery disease in patients scheduled for coronary artery bypass graft (CABG). Design: Retrospective study Setting: Department of Cardiovascular Surgery, University of Health Sciences, Mehmet Akif İnan Training and Research Hospital Subjects: A total of 354 consecutive patients who were scheduled to undergo elective CABG operation Intervention: Predictive values of the variables were measured for atherosclerosis extensity. Main outcome measure(s): The relationship between preoperative NLR-MHR and concomitant arterial disease in patients scheduled to undergo CABG Results: A total number of 310 patients in Group 1 (without additional arterial disease; 64.5% male, mean age: 59.1±8.7 years) and 44 patients in Group 2 (with additional arterial disease; 72.7% male, mean age: 65.5±12.3 years) were recorded in the study. There was a statistical difference between the two groups in terms of age (P=.003) and presence of diabetes mellitus (P=.032). In multivariate analysis, advanced age, NLR and MHR were identified as an independent predictor of concomitant arterial disease. In ROC curve analysis, a cut-off level of 2.85 for predicting concomitant arterial disease was determined for NLR (96% sensitivity and 46% specificity), and for MHR, a cut-off level of 8.65 was determined (90% sensitivity and 42% specificity). Conclusion: In this study, we found that simple blood tests may shed light on the detection of additional arterial diseases in patients planned to undergo CABG.