The Role of Neutrophil-Lymphocyte Ratio and Thrombocyte-Lymphocyte Ratio, Systemic Immune Inflammation Index and Systemic Inflammation Response Index in Identifying Risk Factors in Paediatric Patients with Multiple Surgical Treatments for Septic Arthritis: A Single Centre Study Septik Artrit Nedeniyle Birden Fazla Cerrahi Tedavi Uygulanmış Pediyatrik Hastalardaki Risk Faktörlerini Belirlemede Nötrofil-Lenfosit Oranı ve Trombosit-Lenfosit Oranı ile Sistemik İmmün İnflamasyon İndeksi ve Sistemik İnflamasyon Yanıt İndeksinin Rolü: Tek Merkezli Çalışma
Cocuk Enfeksiyon Dergisi, cilt.19, sa.1, 2025 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 19 Sayı: 1
- Basım Tarihi: 2025
- Doi Numarası: 10.5578/ced.20250101
- Dergi Adı: Cocuk Enfeksiyon Dergisi
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Central & Eastern European Academic Source (CEEAS), CINAHL, EMBASE, TR DİZİN (ULAKBİM)
- Anahtar Kelimeler: Arthritis, infectious, platelet count, lymphocyte count, neutrophils
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Our study aimed to determine the effect of neutro-phil-to-lymphocyte ratio, thrombocyte-to-lymphocyte ratio, systemic immune inflammation index (SII), and systemic inflammation response index (SIRI) in determining risk factors in pediatric patients who had un-derdone more than one surgical treatment for septic arthritis. Material and Methods: The study included patients younger than 16 years of age who were surgically treated for septic arthritis between 2018 and 2022. Blood neutrophil/lymphocyte ratio (NLR), platelet/lym-phocyte ratio (PLR), platelet count x neutrophil count/lymphocyte count ratio (SII), and monocyte count x neutrophil count/lymphocyte count ratio (SIRI) were calculated at admission. Results: Mean age of the 25 patients (10 males, 40%; 15 females, 60%) included in the study was (6.24 ± 4.51) years. The number of patients operated on the hip joint was 6 (24%), and the number of patients operated on the knee joint was 19 (76%). When the type of operation was analyzed, arthroscopic debridement was performed in seven patients (28%) and open debridement in 18 patients (72%) in the first surgical treatment. The number of patients who underwent a second operation was 3 (12%). Conclusion: When comparing mean values of NLR, PLR, SII, and SIRI between patients who underwent multiple surgeries due to septic arthritis and those who had only one surgery, no statistically significant differences were found. Mean C-reactive protein (CRP) levels in patients who had undergone a second surgery were lower than those who had not. However, no significant differences were detected when examining the impact of CRP levels on the necessity of a second surgery.