Aspergillus endocarditis in a patient with acute lymphoblastic leukemia
Turkish Journal of Thoracic and Cardiovascular Surgery, cilt.21, sa.4, ss.1067-1070, 2013 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 21 Sayı: 4
- Basım Tarihi: 2013
- Doi Numarası: 10.5606/tgkdc.dergisi.2013.6801
- Dergi Adı: Turkish Journal of Thoracic and Cardiovascular Surgery
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.1067-1070
- Anahtar Kelimeler: Aspergilloma, Aspergillus endocarditis, infective endocarditis, Ross procedure
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aspergillus endocarditis is a life-threatening condition. Establishment of the diagnosis and treatment remain highly challenging. Aspergillus endocarditis should be suspected in immunocompromised patients with negative blood cultures and vegetation on echocardiography. Definitive diagnosis is based on tissue histology and culture. The best treatment approach requires aggressive surgical debridement in combination with prolonged antifungal therapy. In this article, we report a 5.5-yearold boy with acute lymphoblastic leukemia in whom immunosuppression-related Aspergillus endocarditis developed. The patient underwent a Ross operation and excision of a large vegetation in the left ventricular outflow tract. However, he died due to possible intracerebral abscesses during follow-up.