Iris Changes in Patients with Pediatric Behçet’s Disease: A Cross-sectional Spectral Domain Optical Coherence Tomography Study
Journal of Pediatric Research, cilt.12, sa.4, ss.199-205, 2025 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 12 Sayı: 4
- Basım Tarihi: 2025
- Doi Numarası: 10.4274/jpr.galenos.2025.77642
- Dergi Adı: Journal of Pediatric Research
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.199-205
- Anahtar Kelimeler: Beh & ccedil;et's uveitis, iris area, iris thickness, pediatric Beh & ccedil;et's disease, spectral domain optical coherence tomography
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim: The study aimed to assess whether pediatric Behçet’s disease (PBD) eyes with a history of ocular inflammation in remission exhibit residual iris structural changes compared with BD eyes without ocular involvement and also healthy controls. Materials and Methods: Twenty PBD patients without ocular involvement (Group 1), 6 PBD patients with inactive ocular involvement (Group 2), and 24 age-sex-matched healthy controls (Group 3) were included in this study. Their demographic characteristics and the patients’ anterior and posterior segment examination findings were recorded. Iris thicknesses at 1 mm, 2 mm, and 3 mm from the pupillary margin in the nasal and temporal areas were measured using spectral domain optical coherence tomography (SD-OCT). Iris area measurements in the 3 mm area were evaluated using the ImageJ program. Results: There was no statistical difference between the three groups in terms of their age or gender (p=0.920, p=0.482, respectively). There was no statistically significant difference between the three groups regarding their iris thicknesses at temporal and nasal 1 mm, 2 mm, and 3 mm (p>0.05). The three groups had no significant difference in their temporal and nasal 3 mm area measurements (p>0.05). Conclusion: In PBD eyes with a history of uveitis which were in remission at the time of imaging, iris thickness and area did not differ from those of non-ocular BD eyes or healthy controls. These findings suggest that no persistent iris structural damage is detectable by SD-OCT after the resolution of inflammation, although longitudinal follow-up during both active and inactive phases is warranted.