Effect of combination of uterine artery doppler and vitamin D level on perinatal outcomes in second trimester pregnant women


Tosun G., Akar A. N., Burkankulu D., Ceyhan V., AYDIN E.

Journal of Perinatal Medicine, cilt.53, sa.1, ss.48-57, 2025 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Sayı: 1
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1515/jpm-2024-0274
  • Dergi Adı: Journal of Perinatal Medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CINAHL, EMBASE
  • Sayfa Sayıları: ss.48-57
  • Anahtar Kelimeler: uterine artery Doppler, vitamin D, preeclampsia, premature birth, fetal growth restriction
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Objectives: To investigate the effect of the combination of uterine artery (UtA) Doppler and vitamin D levels on perinatal outcomes in second trimester pregnants was aimed. Methods: UtA Dopplers and vitamin D levels of 226 pregnant women in the second trimester were measured. Patients were followed for adverse pregnancy outcomes. The relationship of this combination with these pregnancy outcomes was evaluated. Results: Sensitivity and specificity values are respectively; Left UtA-S/D ratio for preeclampsia was 85.29 and 81.77 %, left UtA-RI was 90.62 and 43.30 % for preterm birth, and 76.19 and 66.34 % for the development of fetal distress had the best predictive effect. Vitamin D values had no predictive value for any parameter (p>0.005). Conclusions: UtA Doppler has a good predictive value for many adverse pregnancy outcomes. However, in order to correlate these results with second trimester vitamin D levels, more homogeneous and specific groups are needed.