Factors affecting thrombocytopenia during extracorporeal life support used after open heart surgery Açik Kalp Cerrahisi Sonrasi Ekstrakorporeal Yaşam Desteǧi Kullaniminda Trombositopeniye Etki Eden Faktörler
Gogus-Kalp-Damar Anestezi ve Yogun Bakim Dernegi Dergisi, cilt.23, sa.4, ss.121-125, 2017 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 23 Sayı: 4
- Basım Tarihi: 2017
- Doi Numarası: 10.5222/gkdad.2017.121
- Dergi Adı: Gogus-Kalp-Damar Anestezi ve Yogun Bakim Dernegi Dergisi
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.121-125
- Anahtar Kelimeler: ECLS, Extracorporeal circulation, Open Heart Surgery, Thrombocytopenia
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Thrombocytopenia causes unfavourable clinical outcomes after Extracorporeal Life Support (ECLS). ECLS procedure aggravates thrombocytopenia after open heart surgery. The purpose of this study is to explore the possible causes which might contribute to thrombocytopenia developed in patients with ECLS after open heart surgery. Material and Methods: All the patients underwent open heart surgery. ECLS support was provided for the patients who developed low cardiac output syndrome. The patients were grouped as severe, moderate and mild cases with thrombocytopenia according to their platelet levels. Possible risk factors for cardiopulmonary bypass were included in the study. Results: Total number of patients was thirty five. Thirteen (37.1%) of them were women, and twenty-two (62.9%) of them were men. Before ECLS, all of them had undergone cardiopulmonary bypass. Considering preoperative platelet levels, mean (range) platelet count was found as (57-387) 175.97±75.53x103/μL. Twelvepatients (34.3%) with moderate thrombocytopenia had a mean platelet count as 94.0±19.36x103/μL. Twenty three (65.7%) patients had mild and normal thrombocytopenia with a mean platelet count as 218.73±55.26x103/μL. There are no patients who had severe thrombocytopenia. A significant decrease occurred in platelet counts during the postoperative first five days when compared with preoperative counts (p<0.05). Conclusion: Extracorporeal circulation is a risk factor for thrombocytopenia. It has been thought that to prevent severe thrombocytopenia during ECLS usage after open heart surgery, instead of central approach, peripheral approach is more appropriate for cannulation.