Can hyperbilirubinemia be a predictive factor in the diagnosis of acute appendicitis?: A multi-institutional study
Surgical Chronicles, cilt.20, sa.1, ss.225-229, 2015 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 20 Sayı: 1
- Basım Tarihi: 2015
- Dergi Adı: Surgical Chronicles
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.225-229
- Anahtar Kelimeler: Appendicitis, Bilirubin, Diagnosis, Perforated appendicitis
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background/Aim of the Study: In the present study, the researchers investigated whether hyperbilirubinemia could be a predictive factor in the diagnosis of non-perforated acute appendicitis and perforated acute appendicitis. Patients and Methods: A total of 372 cases were included in the study. The cases were classified as normal (Group I), non-perforated acute (Group II), and perforated acute appendicitis (Group III) according to the histopathological diagnoses. Results: There was a statistically significant difference between the groups in terms of duration of hospital stay (p<0.001) and WBC (p<0.001). There was no statistically significant difference in terms of age (p=0.066), total bilirubin(p=0.207),and ALT(p=0.698). There was a statistically significant difference in WBC(p=0.001) and gender(p=0.006) when Group I and Groups II+III were compared. There was no statistically significant difference in age(p=0.061), total bilirubin(p=0.238), AST(p=0.912),and ALT(p=0.285). In the receiver operating characteristic (ROC) curve analysis, there was no statistically significant difference in terms of total bilirubin, and AST/ALT in the patient and control groups. When Group II and Group III were compared to each other, only age was statistically significant(p <0.001). Total bilirubin was not statistically significant(p=0.057). Conclusions:The researchers concluded that hyperbilirubinemia has no diagnostic value in the diagnosis of non-perforated acute appendicitis and perforated acute appendicitis.