Can neutrophil-lymphocyte ratio be a useful criterion for neuroleptic malignant syndrome in the absence of leukocytosis?
Iranian Journal of Psychiatry, cilt.16, sa.3, ss.370-373, 2021 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 16 Sayı: 3
- Basım Tarihi: 2021
- Doi Numarası: 10.18502/ijps.v16i3.6264
- Dergi Adı: Iranian Journal of Psychiatry
- Derginin Tarandığı İndeksler: Scopus, Academic Search Premier, CINAHL, EMBASE, Directory of Open Access Journals
- Sayfa Sayıları: ss.370-373
- Anahtar Kelimeler: Antipsychotic agents, Inflammation, Lymphocyte, Neuroleptic malignant syndrome, Neutrophil
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Neuroleptic malignant syndrome (NMS) is a rare but severe side effect of antipsychotic medication. Neutrophil-lymphocyte ratio (NLR) is a simple marker used to measure systemic inflammation. Method: In this case report we explore the relationship of inflammation in the etiology of NMS. In our case involving NMS, although there was no leukocytosis, the NLR was increased up to systemic infection levels. Conclusion: We hypothesized that systemic inflammation may take a role in developing NMS. If so, NLR could be a new marker of NMS that may be able to provide more sensitive results than leukocyte levels.