The effects of conjugated estrogen, transdermal estradiol and tibolon on lipid profil and cardiovascular risk which used in surgical menopause Cerrahi menopozda kullanilan konjuge ostrojen, transdermal ostradiol ve tibolonun lipid profili ve kardiyovaskuler risk uzerine etkileri
Jinekoloji ve Obstetrik Dergisi, cilt.13, sa.1, ss.30-35, 1999 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13 Sayı: 1
- Basım Tarihi: 1999
- Dergi Adı: Jinekoloji ve Obstetrik Dergisi
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.30-35
- Anahtar Kelimeler: Conjugated estrogen, Menopause, Replacement therapy, Tibolon, Transdermal estradiol
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
OBJECTIVE: In this prospective randomized study it was designed to compare the effects of varying hormone replacement therapies on lipoprotein metabolism and cardiovascular system. STUDY DESIGN: Between 1995-1996, in 90 cases who were undergone hysterectomy and bilateral salpingo-oophorectomy by various indications, were evaluated by the levels of serum lipid with three months intervals. The cases were divided in three groups. Group I 0.625 mg/day conjugated Premarin, was given Group II 50 μg 17β-Estradiol, Group III 2.5 mg Tibolon. The lipid profile was examined at initial visit and three months intervals. RESULTS: It was determined a dimunition of subjective compliances and improvement of the life quality of cases after these regimens. CONCLUSION: We think that, when the basal lipid profile is evaluated, all of these therapies applying for hormone replacement, can prevent the cardiovascular risk which is the most common reason of the death in postmenopausal women.