Feasibility and safety of robot-assisted radical prostatectomy following laser enucleation of the prostate
Central European Journal of Urology, cilt.78, sa.4, ss.532-539, 2025 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 78 Sayı: 4
- Basım Tarihi: 2025
- Doi Numarası: 10.5173/ceju.2025.0123
- Dergi Adı: Central European Journal of Urology
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Central & Eastern European Academic Source (CEEAS), EMBASE
- Sayfa Sayıları: ss.532-539
- Anahtar Kelimeler: laser enucleation of the prostate, benign prostatic obstruction, prostate cancer, robot-assisted radical prostatectomy
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Introduction The aim of this study was to systematically review the available evidence on the feasibility and safety of robot-assisted radical prostatectomy (RARP) in patients with prostate cancer following laser enucleation of the prostate (LEP). Material and methods A systematic search was conducted using PubMed (MEDLINE) and Web of Science online databases until 31 July 2025 with the search terms (“HoLEP” OR “endoscopic enucleation” OR “laser enucleation of the prostate” OR “ThuLEP” OR “ThuFLEP” OR “EEP” OR “LEP”) AND (“robot assisted radical prostatectomy” OR “robotic assisted radical prostatectomy” OR “RARP”) by incorporating the PICO formula (population, intervention, comparison, outcome). Results Three studies were identified. Continence rates and recovery times differed between patients with prior LEP and those who were LEP-naïve. In one study, postoperative incontinence rates were significantly different between the prior HoLEP and HoLEP-naïve groups (74.0% vs 22.0%, p <0.001), whereas in the other two studies there was no significant difference between groups. Erectile function was documented in 2 studies, which exhibited no statistically significant differences between the prior-LEP group and LEP-naïve group. Complication rates across the studies remained relatively low (7.0–9.0%). Biochemical recurrence and positive surgical margins between the previous LEP and LEP naïve groups were comparable. Conclusions In patients undergoing RARP after LEP, complications are low and the oncological outcomes are promising, similar to patients who are LEP-naïve. It is essential for surgeons to counsel patients on the potential for prolonged recovery, particularly in regard to continence and sexual function.