100% HbF Found Thalassemia Intermedia Case in Peripheral Blood Periferik Kanında %100 HbF Bulunan Talasemi İntermedia Olgusu
Genel Tip Dergisi, cilt.31, sa.2, ss.180-181, 2021 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 2
- Basım Tarihi: 2021
- Doi Numarası: 10.15321/geneltipder.2021.310
- Dergi Adı: Genel Tip Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.180-181
- Anahtar Kelimeler: Beta globin gene deletion, HbF, Thalassemia Intermedia
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Hb F is synthesized in the gestational period and the amount decreases gradually with delivery. In an adult person, Hb F is <2%. The affinity of HbF to oxygen is higher than HbA. HbF is therefore not suitable for transporting oxygen to tissues. In this study; We investigated the hematological and biochemical changes in an adult patient with 100% HbF in peripheral blood. Complete blood count of a 66-year-old male patient followed up in hematology clinic with symptoms of anemia; RBC: 3.1 1012 / L, Hb: 8.3 g / dL, Hct: 27.6%, MCV: 90.1 f / L, PLT: 793 000 103 / mm3. Serum ferritin: 1094 ng / mL, total bilirubin: 4 mg / dL, direct bilirubin: 0.68 mg / dL. The hemoglobin variant analysis revealed 100% HbF. The patient had no HbA. The patient was evaluated as thalassemia intermedia.