A newborn with transient diabetes mellitus accompanied by ketoacidosis attributable to a ZFP57 mutation
Journal of Tropical Pediatrics, cilt.63, sa.5, ss.399-401, 2017 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 63 Sayı: 5
- Basım Tarihi: 2017
- Doi Numarası: 10.1093/tropej/fmx005
- Dergi Adı: Journal of Tropical Pediatrics
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.399-401
- Anahtar Kelimeler: ketoacidosis, transient neonatal diabetes mellitus, ZFP57 gene mutation
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Hyperglycemia commencing within the first 6 months of life requires exogenous insulin therapy and, if the condition persists for >2 weeks, is termed neonatal diabetes mellitus (NDM). This rare illness is of two types: transient and permanent NDM. Most cases come to medical attention because of nonspecific symptoms, including intrauterine growth retardation, dehydration, difficulties in feeding and inadequate weight gain. In the present article, we describe an infant who smelt of ketones during examination and who was diagnosed with transient NDM caused by a ZFP57 mutation, accompanied by ketoacidosis. This is the first report of such a condition.