Correlation of neutrophil to lymphocyte ratio with the presence and severity of metabolic syndrome
Clinical and Applied Thrombosis/Hemostasis, cilt.20, sa.2, ss.159-163, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 20 Sayı: 2
- Basım Tarihi: 2014
- Doi Numarası: 10.1177/1076029612459675
- Dergi Adı: Clinical and Applied Thrombosis/Hemostasis
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.159-163
- Anahtar Kelimeler: metabolic syndrome, neutrophil-lymphocyte ratio, inflammation
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Purpose: The aim of this study is to investigate the relationship between the criteria comprising metabolic syndrome (MS) and neutrophil-lymphocyte ratio (NLR), a simple and reliable indicator of inflammation. Method: Seventy patients with MS and 71 age- and sex-matched control participants were included. Patients were classified into 3 groups based on the number of MS criteria: group 1 (with 3 criteria), group 2 (with 4 criteria), and group 3 (with 5 criteria). The NLR was calculated from complete blood count. Results: Patients with MS had significantly higher NLR compared to the control group. Moreover, the group 3 patients had higher NLR than those in groups 2 and 1 (P =.008 and P =.078, respectively), whereas there was no difference between the patients meeting 3 and 4 MS criteria (P =.320). Besides, NLR increased as the severity of MS increased (r =.586, P <.001). The cutoff level for NLR with optimal sensitivity and specificity was calculated as 1.84. Serum glucose and high-sensitive C-reactive protein level were found to be independent predictors of an NLR value greater than 1.84. Conclusion: The present study indicated a significant correlation between the criteria of MS and inflammation on the basis of NLR. Furthermore, there an increase in NLR as the severity of MS increases. © The Author(s) 2012.