The Relationship Between Hemoglobin to Albumin Ratio and Disease-Free Survival in Patients with Locally Advanced Nasopharyngeal Cancer Treated with Chemoradiotherapy Kemoradyoterapi ile Tedavi Edilen Lokal İleri Nazofaringeal Kanserli Hastalarda Hemoglobin-Albümin Oranı ile Hastalıksız Sağkalım Arasındaki İlişki
Medical Journal of Bakirkoy, cilt.21, sa.4, ss.444-448, 2025 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 21 Sayı: 4
- Basım Tarihi: 2025
- Doi Numarası: 10.4274/bmj.galenos.2025.2025.3-8
- Dergi Adı: Medical Journal of Bakirkoy
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, CINAHL, EMBASE, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.444-448
- Anahtar Kelimeler: HAR, DFS, nasopharyngeal cancer, chemoradiotherapy
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: The hemoglobin-to-albumin ratio (HAR) has been linked to survival in various cancers; however, its significance in nasopharyngeal carcinoma (NPC) remains unclear. This study aims to explore the relationship between HAR and disease-free survival (DFS) in NPC patients undergoing concurrent chemoradiotherapy (CRT). Methods: This retrospective study included 30 patients with NPC who received concurrent CRT from January 2018 to December 2024. HAR was calculated as the ratio of hemoglobin to albumin. We performed Cox regression analyses to identify variables associated with DFS. Results: Patients were classified into low- and high-HAR groups using the cut-off value determined by maximally selected rank statistics. DFS was 51.7 months in patients with low HAR and 29.8 months in patients with high HAR. We found a significant relationship between HAR and DFS (p=0.009). Conclusion: A high HAR was associated with a poor prognosis in NPC patients treated with CRT.