Acute massive myelofibrosis with acute lymphoblastic leukemia
Turkish Journal of Hematology, cilt.26, sa.4, ss.204-206, 2009 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 26 Sayı: 4
- Basım Tarihi: 2009
- Dergi Adı: Turkish Journal of Hematology
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.204-206
- Anahtar Kelimeler: Acute myelofibrosis, acute lymphoblastic leukemia, dry tap
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Acute myelofibrosis is characterized by pancytopenia of sudden onset, megakaryocytic hyperplasia, extensive bone marrow fibrosis, and the absence of organomegaly. Acute myelofibrosis in patients with acute lymphoblastic leukemia is extremely rare. We report a 4 1/2-year-old boy who was diagnosed as having acute massive myelofibrosis and acute lymphoblastic leukemia. Performing bone marrow aspiration in this patient was difficult (a "dry tap"), and the diagnosis was established by means of a bone marrow biopsy and immunohistopathologic analysis. The prognostic significance of acute myelofibrosis in patients with acute lymphoblastic leukemia is not clear.