Increased circulating asymmetric dimethylarginine (ADMA) levels in the active stage of Behçet's syndrome
Aktuelle Rheumatologie, cilt.34, sa.2, ss.121-125, 2009 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 34 Sayı: 2
- Basım Tarihi: 2009
- Doi Numarası: 10.1055/s-2008-1027716
- Dergi Adı: Aktuelle Rheumatologie
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.121-125
- Anahtar Kelimeler: Behcet's syndrome, asymmetric dimethylarginine, endothelial dysfunction, thrombosis, active stage
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
There is little evidence in the literature about circulating asymmetric dimethylarginine (ADMA) levels in Behçet's syndrome (BS). The aim of the present study was 1. to measure the levels of ADMA in male patients with BS, 2. to compare ADMA levels with healthy volunteers, and 3. to evaluate whether there is any difference between patients both with/without thrombosis and in active/inactive stage. In patients with BS, CRP levels were higher than controls. The mean ADMA and C-reactive protein (CRP) levels were significantly higher in active stage patients and patients with thrombosis than in patients during the inactive stage and without thrombosis. In conclusion, we did not find any significant difference in ADMA levels between patients with BS and healthy controls. Serum ADMA concentrations, however, were higher in active patients and patients with thrombosis than in patients during the inactive stage and patients without thrombosis. © Georg Thieme Verlag KG Stuttgart.