Do serum vitamin D levels have any effect on intrauterine insemination success?
International Journal of Fertility and Sterility, cilt.12, sa.2, ss.164-168, 2018 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 12 Sayı: 2
- Basım Tarihi: 2018
- Doi Numarası: 10.22074/ijfs.2018.5256
- Dergi Adı: International Journal of Fertility and Sterility
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.164-168
- Anahtar Kelimeler: Infertility, Intrauterine Insemination, Ovulation Induction, Vitamin D
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Recent studies have shown that vitamin D has an essential role in the reproductive system. In this study, we aimed to investigate the effect of vitamin D levels in patients undergoing ovulation induction (OI), and subsequent intrauterine insemination (IUI) procedure. Materials and Methods: One hundred and four infertile and one hundred and three fertile women were recruited in this cross-sectional study which was conducted in a tertiary level maternity hospital. Infertile patients were divided into pregnant and non-pregnant subgroups after treatment. Individual characteristics and 25-hydroxyvitamin D3 [25 (OH) D3] levels were compared between the groups. Results: The vast majority of our study population consisted of women who had vitamin D deficiency (96.6%). There was no statistically significant difference between infertile and fertile groups in terms of serum 25 (OH) D3 levels (P=0.512). Similarly, no significant difference was observed between the pregnant and non-pregnant subgroups of infertile patients regarding 25 (OH) D3 levels (P=0.267). Conclusion: There is no association between female infertility and serum vitamin D levels. Vitamin D does not predict pregnancy in infertile women undergoing OI with IUI. Further research which will provide a comparison between much more women who have deficient and sufficient 25 (OH) D3 levels is warranted.