The relationship between infarct volume and high sensitivity troponin I level in patients diagnosed with ischemic stroke
Irish Journal of Medical Science, cilt.192, sa.2, ss.901-906, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 192 Sayı: 2
- Basım Tarihi: 2023
- Doi Numarası: 10.1007/s11845-022-03048-0
- Dergi Adı: Irish Journal of Medical Science
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, CAB Abstracts
- Sayfa Sayıları: ss.901-906
- Anahtar Kelimeler: Acute ischemic stroke, Emergency, GKS, High sensitive troponin I, Mortality
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Various biomarkers and clinical variables are used to determine the probability risk, diagnosis, and the prognosis of acute ischemic stroke, but effective markers are still warranted. Aim: We aimed to determine the effectiveness of Hs-cTnI levels to predict the prognosis of AIS. Methods: This study was planned as a retrospective observational study. Patients with available data and over 18 years old were included in the study. Diffusion magnetic resonance images were evaluated by a senior radiologist and the infarct size was calculated. Results: We included 110 (54.2%) males and 93 (45.8%) females; a total of 203 patients with a mean age of 68.9 were included in the present study. Patients were divided into two groups according to the cut-off level of Hs-troponin-I (group I: lower than 8.5 mg/dL; group 2: higher than 8.5 mg/dL). These two groups were compared for mortality and infarct volume. Infarct volume and the mortality ratio of the group 2 was significantly higher [p = 0.041, U = 4294.5, LV = 6.5 (IQR = 1.8–25.4)]. Conclusions: Hs-troponin I may be an effective biomarker in predicting the prognosis of patients with acute ischemic stroke. Multicenter comprehensive prospective studies are warranted to obtain stronger results.