Flurbiprofen-induced generalized bullous fixed drug eruption
Human and Experimental Toxicology, cilt.33, sa.1, ss.106-108, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 1
- Basım Tarihi: 2014
- Doi Numarası: 10.1177/0960327113489048
- Dergi Adı: Human and Experimental Toxicology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.106-108
- Anahtar Kelimeler: Fixed drug eruption, flurbiprofen, generalized, bullous
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Fixed drug eruption (FDE) is an unusual drug-related side effect that results in recurrent lesions whenever the causative drugs are used. FDEs usually occur as a single, sharply demarcated, round erythematous patch or plaque, occasionally with localized bullae. The most common offending agents include antimicrobials, nonsteroidal anti-inflammatory drugs, and antiepileptics. There are some reports where contact dermatitis and cutaneous vasculitis have been associated with the use of flurbiprofen. We present the case of a 50-year-old man with flurbiprofen-induced generalized bullous FDE. To the best of our knowledge, the most serious form of FDE, the generalized bullous FDE, to be caused by flurbiprofen has not been reported previously. © The Author(s) 2014.