Prolonged Bleeding after Dental Extraction Due to Decreased Serum Level of von Willebrand Factor Caused by Untreated Profound Hypothyroidism
Journal of Pediatric Hematology/Oncology, cilt.45, sa.5, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 45 Sayı: 5
- Basım Tarihi: 2023
- Doi Numarası: 10.1097/mph.0000000000002617
- Dergi Adı: Journal of Pediatric Hematology/Oncology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, MEDLINE
- Anahtar Kelimeler: hypothyroidism, Hashimoto's thyroiditis, decreased von willebrand factor
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Delayed diagnosis of hypothyroidism may result in atypical presentations. Here, we report a case with decreased serum level and activity of von Willebrand factor due to untreated profound hypothyroidism Observation: A 9-year-old girl, presented with prolonged gingival bleeding after dental extraction. Clinical findings of the case were consistent with hypothyroidism, and the laboratory workup results revealed decreased serum level and activity of von Willebrand factor associated with profound hypothyroidism. Restoration of euthyroidism normalized the coagulation parameters. Conclusion: Delayed diagnosis of hypothyroidism may lead to atypical presentations such as bleeding diathesis. Profound hypothyroidism should be considered in the differential diagnosis of acquired von Willebrand disease to avoid undue treatment.