The prognostic value of the nutritional prognostic index (NPI) and controlling nutritional status (CONUT) scoring systems in non-ST elevated myocardial infarction patients over 65 years of age
Aging Clinical and Experimental Research, cilt.34, sa.3, ss.555-562, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 34 Sayı: 3
- Basım Tarihi: 2022
- Doi Numarası: 10.1007/s40520-021-02039-y
- Dergi Adı: Aging Clinical and Experimental Research
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Abstracts in Social Gerontology, AgeLine, CAB Abstracts, CINAHL, EMBASE, MEDLINE
- Sayfa Sayıları: ss.555-562
- Anahtar Kelimeler: Non-ST elevated myocardial infarction, Inflammation, Malnutrition, Aged
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Nutritional status and metabolic responses to inflammation changes with age and comorbid conditions. Aims: We aimed to compare the predictive values of the nutritional prognostic index (NPI) and controlling nutritional status (CONUT) Score systems with the GRACE score in elderly (non-ST elevated myocardial infarction) NSTEMI patients. Methods: NSTEMI patients over 65 years of age have been included in this study. The factors affecting mortality were determined by regression analysis. ROC curve analysis were performed and predictiveness of the scores was tested. Results: Mean age of patients was 74.49 ± 7.60 years, median GRACE and NPI scores were 118 (107–131.50 IQR) and 50.10 (45.30–54.27 IQR), respectively, and CONUT scores ≥ 3 were 24.4% of all patients. 32 (15.6%) patients died within 6 months. White blood cells and albumin levels maintain their significance in the multivariate regression analysis (OR: 1.386; 0.025, p < 0.001, respectively). ROC curve analysis of NPI, CONUT, Killip, and GRACE scores were performed (AUC: 0.757; 0.744; 0.725; 0.800, p < 0.001, respectively). Discussions: The frequency of NSTEMI increases with the effect of increasing age and comorbid conditions. The NPI and CONUT scoring systems have been tested in many previous studies to predict the prognosis of both malignancy and cardiovascular diseases. What makes this scoring system valuable for our study is the thought that our study group will be more prone to malnutrition because they are old and present with an acute presentation. Conclusions: NPI and CONUT scoring systems have been successful at rates approaching the GRACE score system, which is used primarily to predict the prognosis of NSTEMI.