Status of vitamin D among Turkish adults with type 2 diabetes mellitus in primary health care
Acta Medica Mediterranea, cilt.31, sa.2, ss.229-236, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 2
- Basım Tarihi: 2015
- Dergi Adı: Acta Medica Mediterranea
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.229-236
- Anahtar Kelimeler: Type 2 diabetes mellitus, vitamin D, HbAlc, insulin sensitivity, 25(OH)D
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Aims: The aim of our study was to investigate the prevalence and correlates of 25-hydroxy vitamin D (25(OH)D) deficiency and the relationship between 25(OH)D and the type 2 diabetes mellitus (T2DM) in primary health care. Materials and methods: One hundred and thirty four Turkish adults with T2DM from the Family Medicine outpatient clinic and 134 non-diabetic, healthy controls were included in the study. We measured serum 25(OH)D, calcium, low density lipoprotein (LDL), insulin, parathormone (PTH) and blood fasting glucose and compared the results between the T2DM group and matched healthy control subjects. Results: Both the T2DM and healthy groups had vitamin D deficiency. The mean age for those with T2DM was 58.00 ± 12.03 years versus 46.76 ± 15.70 years among the controls. The mean levels of 25(OH)D were significantly lower in the T2DM adults than in the controls (11.85 ± 8.51 ng/ml versus 15.33 ± 17.42 ng/ml). In the T2DM adults, 35.8% were mildly (10-20 ng/ml), 35.8% were moderately (5-10 ng/ml), and 17.2% were severely (<5 ng/ml) vitamin D deficient as compared with 26.1% (mildly), 41.8% (moderately), and 11.9% (severely) in the control group. Overall, 88.8% of the T2DM patients and 79.9% of the healthy controls were vitamin D deficient. Conclusion: This study demonstrated prevalent vitamin D deficiency in patients with T2DM and normal subjects. The population in our study was generally deficient in 25(OH)D indicating a greater need for vitamin D supplementation.