MRI-based texture analysis to differentiate the most common parotid tumours
Clinical Radiology, cilt.75, sa.11, 2020 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 75 Sayı: 11
- Basım Tarihi: 2020
- Doi Numarası: 10.1016/j.crad.2020.06.018
- Dergi Adı: Clinical Radiology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
AIM: To evaluate magnetic resonance imaging (MRI) features and signal characteristics of parotid masses and investigate the added role of texture analysis (TA) in the differentiation of parotid tumours. MATERIALS AND METHODS: Ninety-five patients (42 women, 53 men; mean age 51.67±14.15) were included in this study. The study group consisted of 40 pleomorphic adenoma, 45 Warthin's tumour, and 10 mucoepidermoid carcinomas. Two reviewers assessed the MRI sequences retrospectively. Fat-suppressed T2-weighted and contrast-enhanced T1-weighted axial images were used for TA. Receiver operating characteristic curve analyses were performed to evaluate the ability to make a diagnosis. Logistic regression analyses were conducted to explore the independent risk factors among the MRI features and to analyse the added value of TA to the qualitative analysis. RESULTS: Significant differences were found in the tumour border (p<0.001), infiltration of the surrounding tissue (p=0.003), contrast-enhancement grading (p<0.001), perineural spread (p=0.013), and pathological lymph nodes (p<0.001) between the malignant and benign tumours. Kurtosis on contrast-enhanced T1-weighted images, and skewness and kurtosis on T2-weighted images were significantly different between the three groups (p=0.020, <0.001, 0.003; respectively). A kurtosis value on T2-weighted images <2.815 along with an ill-defined border had the highest specificity (98.8%) and positive predictive value (83.3%) in the differentiation of malignant tumours. CONCLUSION: The addition of TA parameters to the MRI findings may contribute to distinguish benign from malignant parotid tumours.