Relationship between bone mineral density and clinical features in patients with inflammatory bowel disease: A local study in Turkish population
Journal of International Medical Research, cilt.38, sa.1, ss.62-68, 2010 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 38 Sayı: 1
- Basım Tarihi: 2010
- Doi Numarası: 10.1177/147323001003800107
- Dergi Adı: Journal of International Medical Research
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.62-68
- Anahtar Kelimeler: INFLAMMATORY BOWEL DISEASE, CROHN'S DISEASE, ULCERATIVE COLITIS, OSTEOPOROSIS, CORTICOSTEROIDS, BONE MINERAL DENSITY, BODY MASS INDEX
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
This study aimed to compare the bone mineral density (BMD) of patients with ulcerative colitis (UC) and Crohn's disease (CD) in order to determine the possible risk factors for bone loss. A total of 142 patients with UC (n = 88) and CD (n = 54) participated in the study. They were assessed for gender, body mass index (BMI), disease duration and activity, intestinal site of involvement, history of bowel resection, use of steroids, and extra-intestinal findings and complications. The BMD was measured by dual-energy X-ray absorptiometry. There were no differences in BMD between UC and CD patients. In UC patients, BMI showed a significant positive correlation with BMD. Femoral neck Z scores were lower in patients with extra-intestinal findings and complications. Steroid use, disease activity, disease localization, disease duration, bowel surgery and gender had no influence on BMD. Complications or extra-intestinal involvement were a significant predictor for BMD in both groups. Copyright © 2010 Field House Publishing LLP.