Borderline-resectable Undifferentiated Carcinoma with Osteoclast-like Giant Cells of the Pancreas: upfront Surgery or Neoadjuvant Chemotherapy?
Journal of the College of Physicians and Surgeons Pakistan, cilt.32, sa.7, ss.934-937, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 32 Sayı: 7
- Basım Tarihi: 2022
- Doi Numarası: 10.29271/jcpsp.2022.07.934
- Dergi Adı: Journal of the College of Physicians and Surgeons Pakistan
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
- Sayfa Sayıları: ss.934-937
- Anahtar Kelimeler: Neoadjuvant chemotherapy, Pancreatic neoplasms, Undifferentiated carcinoma, giant cells, Pancreaticoduodenectomy
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Undifferentiated carcinoma with osteoclast-like giant cells (UDC-OGC) of the pancreas is an extremely rare entity, thus an obvious discrepancy regarding their treatment approach exists in the current literature. A 52-year female patient with a two-weeks history of jaundice was diagnosed as borderline-resectable pancreatic mass located in the uncinate process of a size of 5×4 cm. Pancreaticoduodenectomy (PD) with partial portal vein resection was successfully performed following neoadjuvant chemotherapy (NACT). The pathology was interpreted as UDC-OGC without lymph node involvement. Considering their aggressive behavior, NACT followed by surgery seems to be a good option in case of borderline-resectable UDC-OGC.