Evaluation of Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio and Mean Platelet Volume in Patients with Hypothyroidism Hipotiroidizmli Hastalarda Nötrofil-Lenfosit Oranı, Trombosit Lenfosit Oranı ve Ortalama Trombosit Hacminin Değerlendirilmesi
Eurasian Journal of Family Medicine, cilt.9, sa.3, ss.139-146, 2020 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 9 Sayı: 3
- Basım Tarihi: 2020
- Doi Numarası: 10.33880/ejfm.2020090304
- Dergi Adı: Eurasian Journal of Family Medicine
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.139-146
- Anahtar Kelimeler: hypothyroidism, lymphocytes, mean platelet volume, Neutrophils, platelets
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim: Our aim was the evaluation of neutrophil-lymphocyte ratio, platelet lymphocyte ratio and mean platelet volume levels in the patient and control groups with hypothyroidism. Methods: Our study was conducted with 111 participants; 68 patients and 43 healthy individuals as the control group. Thyroid hormones, lipid panel and hemogram levels of the participants were examined. Neutrophil-lymphocyte ratio, platelet lymphocyte ratio and mean platelet volume levels were calculated. Results: Neutrophil-lymphocyte ratio, platelet lymphocyte ratio and mean platelet volume levels were similar between the patients with subclinical and overt hypothyroidism and the control group. A positive correlation was found between neutrophil-lymphocyte ratio and platelet lymphocyte ratio. A negative correlation was found between platelet lymphocyte ratio and mean platelet volume. While there was no relationship between thyroid stimulating hormone and neutrophil-lymphocyte ratio, platelet lymphocyte ratio and mean platelet volume; a negative correlation was found between neutrophil-lymphocyte ratio and free thyroxine. Conclusion: Neutrophil-lymphocyte ratio, platelet lymphocyte ratio and mean platelet volume levels were similar in the hypothyroidism and control groups. We believe that prospective studies that evaluate neutrophil-lymphocyte ratio, platelet lymphocyte ratio and mean platelet volume together with other inflammatory parameters are needed to predict the risk of microinflammation and cardiovascular disease in patients with hypothyroidism.