Investigation of the effects of antibiotic and single doses steroid application in cases of preterm premature rupture of membranes Preterm erken membran rüptürü olgularinda antibiyotik tedavisi i̇le birlikte tek doz steroid kullaniminin etkilerinin araştirilmasi

Kumru S., Gurates B., Şimşek M., SAPMAZ E., Parmaksiz C., Aygün D.

Jinekoloji ve Obstetrik Dergisi, cilt.18, sa.4, ss.232-235, 2004 (Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 4
  • Basım Tarihi: 2004
  • Dergi Adı: Jinekoloji ve Obstetrik Dergisi
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.232-235
  • Anahtar Kelimeler: Antibiotic, Preterm Premature Rupture of Membranes, Steroid
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

PURPOSE: Investigation of the effects of antibiotic and steroid treatment on maternal and perinatal outcomes in preterm premature rupture of membranes (pPROM) cases. STUDY DESIGN: This study was undertaken in Firat University Medical School Department of Obstetric and Gynecology between January-December 2003. The study groups were consist of thirty three cases hospitalized and treated as pPROM. The patients in group I (n=16) were treated with antibiotic (ampicillin) alone, and the patients in group II were given single dose steroid (betamethasone) in addition to antibiotic. Maternal and perinatal outcomes were compared. RESULTS: Demographic characteristics of the study groups were similar. Latent periods elapsed from pPROM to delivery, the incidence of chorioamnionitis and endometritis were not different between two groups (p>0.05). Although, the incidences of respiratory distress syndrome were 18% in group I and 5% in group II this differences was not statistically significant (p>0.05). While isolette and newborn intensive care unit requirements were 43% vs. 23% and 23% vs. 12% in group I and group II, respectively; these findings were not different between two groups (p>0.05). CONCLUSION: Single dose steroid application together with antibiotic has no adverse effect on maternal and perinatal outcomes in cases of pPROM, produce a tendency reduced newborn morbidity.