Which factors determine exocrine pancreatic dysfunction in diabetes mellitus?
World Journal of Gastroenterology, cilt.25, sa.22, ss.2699-2705, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 25 Sayı: 22
- Basım Tarihi: 2019
- Doi Numarası: 10.3748/wjg.v25.i22.2699
- Dergi Adı: World Journal of Gastroenterology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.2699-2705
- Anahtar Kelimeler: Exocrine pancreas, Diabetes mellitus, Fecal elastase, Malabsorption, Chronic complication
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
The exocrine structure is significantly affected by diabetes because of endocrine structure-function disorder within the pancreas. Exocrine pancreatic dysfunction (EPD) is the general name of the malabsorption process resulting from inadequate production, release, decreased activation, and/or insufficient degradation of enzymes required for digestion from pancreatic acinar cells. It is important to diagnose patients early and correctly, since there may be both macro- and micro-nutrient deficiency in EPD. In this paper, EPD, the diabetes-EPD relationship, and the predictive, effective factors affecting the emergence of EPD are briefly explained and summarized with contemporary literature and our experienced based on clinical, lab, and radiological findings.