The effect of glutamine on colon anastomosis KOLON ANASTOMOZLARINA GLUTAMININ ETKISI


Erbil Y., Seven R., KOCATAŞ A., Bozbora A., Bilgic L., Dinccag A.

Istanbul Tip Fakultesi Mecmuasi, cilt.58, sa.1, ss.33-36, 1995 (Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 58 Sayı: 1
  • Basım Tarihi: 1995
  • Dergi Adı: Istanbul Tip Fakultesi Mecmuasi
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.33-36
  • Sağlık Bilimleri Üniversitesi Adresli: Hayır

Özet

Glutamine, known as the energy source of epithelial cells, is used in total parenteral nutrition. Due to the increasing effect of colonocytes proliferation; glutamine is considered in colonic anastomosis recently. In our study enteral diet with and without glutamine was applied to the rots with colon anastomosis to investigate the biomechanical, biochemical and histopathologic results. No significant difference was found between the two groups in respect of the biomechanic and histopathologic result (p<0.5). A significant increase was found in the hydroxyproline levels of the rats using glutamine (p<0.001). The results of our study show that the enteral use of glutamine is effective on colon anastomosis.