Hepatitis agents with enteric transmission - An epidemiological analysis
Infection, cilt.30, sa.6, ss.334-337, 2002 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 30 Sayı: 6
- Basım Tarihi: 2002
- Doi Numarası: 10.1007/s15010-002-2123-0
- Dergi Adı: Infection
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.334-337
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Background: Viral hepatitis is characterized by special clinical, biochemical and serological findings. This study was planned to determine the seroprevalence, epidemiological characteristics and clinical and biochemical findings of hepatitis A virus (HAV) and hepatitis E virus (HEV) infections during an outbreak of jaundice. Materials and Methods: 340 children aged 5-16 years were included. Clinical findings and alanine aminotransferase (ALT) levels were documented. Anti-HAV IgG and IgM in addition to anti-HEV IgG and IgM were determined by microELISA. Results: Clinical findings, high levels of ALT, anti-HAV IgM and IgG, anti-HEV IgM and IgG were present in 6%, 23%, 17%, 100%, 7% and 9% of cases, respectively. The relationship between ALT levels and anti-HAV or anti-HEV IgM seropositivity was significant (p ≤ 0.0001). Conclusion: HAV and HEV infection were both caused by a contaminated water supply.