The effect of midazolam premedication to intravenous cannulation with topical lidocaine-prilocaine cream (EMLA) in pediatric patients Çocuklarda topikal lidokain-prilokain kremle (EMLA) intravenöz kanülasyona oral midazolam premedikasyonunun etkisi
Pediatrik Cerrahi Dergisi, cilt.17, sa.1, ss.12-16, 2003 (Scopus)
- Yayın Türü: Makale / Özet
- Cilt numarası: 17 Sayı: 1
- Basım Tarihi: 2003
- Dergi Adı: Pediatrik Cerrahi Dergisi
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.12-16
- Anahtar Kelimeler: EMLA cream, Midazolam, Pediatric, Premedication
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim: Midazolam premedication and EMLA cream (Eutectic Mixture of local anesthetics; Astra USA, Westborough, MA) topical anesthesia are frequently used in invasive procedures in pediatric patients. In this study, we aimed to investigate the effect of midazolam premedication to intravenous cannulation with EMLA cream. Method: 1-12 years old 62 patients with ASA I-II and institutional approval and parents' consent were included in the study. They were divided into four groups in according to their age and the drugs used. Group A1: 1-5 years, EMLA (n=14) Group A2: 1-5 years, EMLA+midazolam (n=15) Group B1: 6-12 years, EMLA(n=17) and Group B2: 6-12 years, EMLA+midazolam (n=16). EMLA was applicated to the dorsum of the hand, one hour before the operation. Midazolam 0.5 mg/kg was given orally diluted in clear fruit juice, 30 minutes before the procedure. The reaction to give hand during venepuncture with 22G cannula and drawing hand during injection were classified as 0=non, 1=mild and 2=severe. Injection pain was measured with face scale and observation pain scale scores renging between one to five. Results: While the score used to evaluate stress and anxiety was significantly higher (p<0.05) in the A, group compared to others, there was no difference among the three other groups. The results of the hand withdrawal at injection scale and observation pain scale that are used to evaluate the efficacy of EMLA cream, were similar in all groups (p>0.05). In group A1 the reaction to give hand was significantly high compared to other groups. There was no difference among hand with drawl at injection among all groups. Conclusion: We conclude that in older children preoperative briefing and EMLA cream application provides satisfactory comfort in minor procedures such as intravenous connulation while younger children should be given midazolam premedication in addition to EMLA cream application.