Impact of bicuspid aortic valve on complications and death in infective endocarditis of native aortic valves
Texas Heart Institute Journal, cilt.36, sa.2, ss.111-116, 2009 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 36 Sayı: 2
- Basım Tarihi: 2009
- Dergi Adı: Texas Heart Institute Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.111-116
- Anahtar Kelimeler: Aortic valve/abnormalities/pathology/ultrasonography, aortic valve insufficiency/classification/diagnosis, echocardiography/methods, endocarditis, bacterial/complications/mortality/pathology/ultra-sonography, heart defects/congenital, heart diseases/complications, heart valve diseases/classification/complications/congenital/pathology, hospital mortality, retrospective studies, risk factors
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
We retrospectively investigated the impact of bicuspid aortic valve on the prognosis of patients who had definite infective endocarditis of the native aortic valve. Of 51 patients, a bicuspid aortic valve was present in 22 (43%); the other 29 had tricuspid aortic valves. On average, the patients who had bicuspid valves were younger than those who had tricuspid valves. Patients with a tricuspid valve had larger left atrial diameters and were more likely to have severe mitral regurgitation. Periannular complications, which we detected in 19 patients (37%), were much more common in the patients who had a bicuspid valve (64% vs 17%, P=0.001). The presence of a bicuspid valve was the only significant independent predictor of periannular complications. The in-hospital mortality rate in the bicuspid group was lower than that in the tricuspid group; however, this figure did not reach statistical significance (9% vs 24%, P=0.15). In multivariate analysis, left atrial diameter was the only independent predictor associated with an increased risk of death (hazard ratio, 2.19; 95% confidence interval, 1.1-4.5; P=0.031). In our study, patients with infective endocarditis in a bicuspid aortic valve were younger and had a higher incidence of periannular complications. Although a worse prognosis has been reported previously, we found that infective endocarditis in a native bicuspid aortic valve is not likely to increase the risk of death in comparison with infective endocarditis in native tricuspid aortic valves. © 2009 by the Texas Heart® Institute.