Photoprevention with Oral Polypodium leucotomos Extract and Treatment with Medium-Depth Chemical Peeling in Xeroderma Pigmentosum: A Case Report


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AKOĞLU G., Tecik A.

Turkish Journal of Dermatology, cilt.19, sa.2, ss.107-110, 2025 (ESCI, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 2
  • Basım Tarihi: 2025
  • Doi Numarası: 10.4274/tjd.galenos.2025.15807
  • Dergi Adı: Turkish Journal of Dermatology
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Central & Eastern European Academic Source (CEEAS), CINAHL, EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.107-110
  • Anahtar Kelimeler: Actinic keratosis, chemexfoliation, xeroderma pigmentosum, polypodium
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Early diagnosis of xeroderma pigmentosum (XP) is mandatory to establish adequate sun protection, and regular examinations to detect and treat the premalignant and malignant overgrowths as early as possible. Aqueous extract from the leaves of Polypodium leucotomos (PLE) attracts attention due to its photopreventive and anticarcinogenic properties; however, more experience is needed in patients with XP. Chemical peelings help to rejuvenate the photodamaged and cancer-prone skin. However, data about their use in patients with XP is scarce. Herein, we discuss our experience with oral PLE extract and medium-depth peeling in a 34-year-old female patient with XP and the treatment outcomes.