Adult-onset subacute sclerosing panencephalitis presenting with tonic motor seizures
International Journal of Neuroscience, cilt.131, sa.9, ss.914-918, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 131 Sayı: 9
- Basım Tarihi: 2021
- Doi Numarası: 10.1080/00207454.2020.1759584
- Dergi Adı: International Journal of Neuroscience
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE, Psycinfo
- Sayfa Sayıları: ss.914-918
- Anahtar Kelimeler: SSPE, tonic seizure, adult-onset
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Purpose/aim of the study: Subacute sclerosing panencephalitis (SSPE) is a degenerative disease of the brain caused by a persistent measles virus infection occurring mostly in childhood or early adolescence. The spectrum of epileptic phenomena associated with SSPE is wide, varying from partial or generalized tonic-clonic seizures and atypical absences to myoclonic-atonic attacks. Tonic seizures are very rare in SSPE. Materials and methods: Herein, we discuss a case of 25 years old male that presented with adult-onset SSPE with tonic seizures accompanying myoclonic seizures. Results: Patient was treated with clonazepam 5 mg/day and an isoprinosine regimen with a dose of 70 mg/kg/day. This is the fourth case of SSPE presenting with myoclonic and tonic seizures and the first case of SSPE with myoclonic and tonic seizures reported in an adult-onset case in the English literature. Conclusions: Adult-onset SSPE with tonic seizures is rare and may be confusing, thus, it is important to recognize the presence of this type of tonic motor seizures in SSPE patients.