A novel scoring system (YASHMA) predicting brain injury in asphyxiated newborns
Journal of Tropical Pediatrics, cilt.68, sa.6, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 68 Sayı: 6
- Basım Tarihi: 2022
- Doi Numarası: 10.1093/tropej/fmac082
- Dergi Adı: Journal of Tropical Pediatrics
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, CAB Abstracts, CINAHL, EMBASE, Index Islamicus, MEDLINE, Veterinary Science Database
- Anahtar Kelimeler: newborn, perinatal asphyxia, hypoxic-ischemic encephalopathy, brain injury
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Hypoxic-ischemic encephalopathy is a complication of adverse intrapartum events and birth asphyxia resulting in brain injury and mortality in late preterm and term newborns. Objectives: In this study, we aimed to predict brain damage on magnetic resonance imaging (MRI) with a new scoring system. Methods: Yieldly And Scorable Holistic Measuring of Asphyxia (YASHMA) is generated for detection of brain injury in asphyxiated newborns. Total scores were calculated according to scores of birth weight, gestation weeks, APGAR scores at first and fifth minutes, aEEG patterns and epileptic status of patients. The major outcome of the scoring system was to determine correlation between poor scores and neonatal brain injury detected on MRI. Results: In hypothermia group with brain injury, low gestational weeks and lowest APGAR scores, abnormal aEEG findings were statistically different from others. YASHMA scores were statistically significant with high sensitivity, specificity, AUC and 95% confidence interval values. Conclusions: YASHMA scoring system is feasible and can be suggestive for detecting brain injury in low-income countries.