Usage areas of silica and possıble toxic effects due to silica exposure Silikanın kullanım alanları ve silika maruziyetine bağlı olası toksik etkiler


Anlar H. G., GÜDÜL BACANLI M., Başaran N.

Hacettepe University Journal of the Faculty of Pharmacy, cilt.39, sa.1, ss.17-29, 2019 (Scopus)

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 39 Sayı: 1
  • Basım Tarihi: 2019
  • Dergi Adı: Hacettepe University Journal of the Faculty of Pharmacy
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.17-29
  • Anahtar Kelimeler: Cancer, Occupational exposure, Silicon dioxide, Silicosis, Tuberculosis
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

The earth’s crust contains approximately 12% free crystalline silica and silicon (Si) is the second most common element after oxygen. Therefore exposures to crystalline silica dust might occur in a large variety of occupations, including metal foundries, constructions and ceramic, quarry, pottery industries. Crystalline silica exposure has been linked with silicosis, lung cancer and other pulmonary diseases. In recent years, studies conducted with silica-exposed workers have claimed that silica exposure have caused other cancers such as gastric, nasopharyngeal, salivary gland cancer, liver cancer, bone cancer and brain cancer. Crystalline silica dust exposure in workers is still considered to be important health problem especially in developing countries. This review aims to give a brief summary of the current information about usage and toxic effects of silica in humans and up date regulations about cristalline silica exposure in our country.