Thyroid function and recurrence rate following surgical treatment of nontoxic goitre: Preliminary findings
Gazi Medical Journal, cilt.8, sa.2, ss.72-79, 1997 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 8 Sayı: 2
- Basım Tarihi: 1997
- Dergi Adı: Gazi Medical Journal
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.72-79
- Anahtar Kelimeler: Recurrence, Thyroid Function, Thyroid Resection, Thyroxine
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Purpose: Postoperative thyroid functions and recurrences of a selected group of our patients treated surgically for nontoxic multinodular goitre were documented and discussed from the stand point of the extent of surgery and prophylactic thyroxine. Methods: A total of 81 patients was grouped according to the remnant size and followed for an average of 58 months (4.8 years). Results : The results of our study suggest that; i) subtotal thyroidectomy is not promising for the postoperative maintenance of normal thyroid functions because about 1/3 of the patients with remnants of 6-10 g develops hypothyroidism postoperatively; ii) the unacceptably high recurrence rate after bilateral subtotal lobectomy is reduced by the postoperative administration prophylactic thyroxine; iii) the short term recurrence rate is low when bilateral near total resection is performed; iv) in spite of the normal TSH levels, patients with unilateral lobectomies have a high risk of developing nodules in the previously normal lobe, and therefore require additional preventive measures. Conclusion: Altogether, our results weigh in favor of performing more radical resections for nontoxic nodular goitre and utilizing the prophylactic effect of thyroxine in patients coming from endemic regions.