Effects of preeclampsia on the amplitude integrated electroencephalography activity in preterm infants
Journal of Perinatal Medicine, cilt.44, sa.3, ss.345-349, 2016 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 44 Sayı: 3
- Basım Tarihi: 2016
- Doi Numarası: 10.1515/jpm-2015-0096
- Dergi Adı: Journal of Perinatal Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.345-349
- Anahtar Kelimeler: aEEG, cerebral blood flow, preeclampsia, preterm
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Preeclampsia leads to chronic intrauterine hypoxia by interfering with placental blood supply. The aim of this study was to investigate whether preeclampsia exposure has an influence on the central nervous system of infants, as monitored by amplitude integrated electroencephalography (aEEG). Methods: We recruited 52 infants with gestational age between 30 and 34 weeks. Twenty-seven infants were born to preeclamptic mothers, and 25 gestational age-matched infants whose mothers were healthy were enrolled as a control group. aEEG recordings were performed between 24 and 48 h of life using a cerebral function monitor (CFM) (Olympic Brainz monitor). Along with aEEG, middle cerebral artery (MCA) blood flow velocities (BFV) were measured using Doppler ultrasound. Results: The duration of quiet sleep was significantly shorter (P=0.001), and Burdjalov score was lower (P=0.04) in the preeclampsia group. However, there was no change in MCA BFV in this group. Conclusions: Preeclampsia altered cerebral electrical activity of premature infants born to preeclamptic mothers.