The relationship of prognostic nutritional index with prognosis and inflammation in patient with heart failure and reduced ejection fraction
Nutrition and Health, cilt.29, sa.4, ss.737-743, 2023 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 29 Sayı: 4
- Basım Tarihi: 2023
- Doi Numarası: 10.1177/02601060221103017
- Dergi Adı: Nutrition and Health
- Derginin Tarandığı İndeksler: Scopus, ASSIA, BIOSIS, CAB Abstracts, CINAHL, Food Science & Technology Abstracts
- Sayfa Sayıları: ss.737-743
- Anahtar Kelimeler: Heart failure, prognostic nutritional index, prognosis, inflammation
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Malnutrition is closely associated with heart failure, and known to be closely associated with mortality and morbidity in these patients. Aims: We investigated the relationship of the prognostic nutritional index (PNI), which is a criterion of nutritional status in patients with heart failure with reduced ejection fraction (HFrEF), with prognosis and parameters indicating inflammation. Methods: 139 patients admitted to the coronary intensive care unit with symptoms of decompensated congestive heart failure were included to the study. Patients were with heart failure with ejection fraction <%40 and decompensated for any reason. Patients who died within 1 year in hospital or follow-up were considered to have reached the endpoint. Groups were divided into 2 groups as Group 1, the exitus; (23 patients, 7 M, mean age; 69.2 ± 15.0 years) and group 2, the non-exitus; (116 patients, 57 M, mean age; 69.3 ± 11.5 years). PNI was calculated with the formula ALB(g/L) + 5 × Total lymphocyte count(109/L). Results: PNI was significantly lower in group 1. Neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and systemic inflamatory index values were significantly higher in group 1. PNI was significantly associated with these parameters. Conclusion: Low PNI scores in HFrEF patients may be associated with a worse prognosis and hematological parameters indicating more negative inflammation. PNI was found to be an independent predictor of mortality.