COVID-19 Disease in Kidney Transplant Recipients Enfermedad por COVID-19 en receptores de trasplante renal
Revista de Nefrologia, Dialisis y Trasplante, cilt.42, sa.3, ss.181-188, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 42 Sayı: 3
- Basım Tarihi: 2022
- Dergi Adı: Revista de Nefrologia, Dialisis y Trasplante
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Fuente Academica Plus, EMBASE, Directory of Open Access Journals, DIALNET
- Sayfa Sayıları: ss.181-188
- Anahtar Kelimeler: clinical course, COVID-19, kidney transplantation
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim: Coronavirus infection can lead to severe acute respiratory distress syndrome. Information on COVİD-19 infection in patients with kidney transplants (KT) is lacking yet. In our study, clinical, radiological, laboratory features and clinical course of COVİD-19 infection in these patients were investigated. Methods: We retrospectively investigated KT recipient patients with COVID-19 diagnosed between March 15, 2020, and December 15, 2020. Clinical, radiological, laboratory features and clinical course of COVID-19 infection in these patients were recorded. Results: We identified 23 KT recipient patients with COVID-19 infection. Eighteen KT patients (78.3%) had positive reverse transcription polymerase chain reaction (RT-PCR) results for COVID-19, 5 patients (21.7%) were negative. Twelve KT patients (52.2%) were male and 11 (47.8%) were female. Fifteen of the KT patients (65.2%) had comorbidity. Thorax computed tomography showed infiltrations in 21 KT patients (91.3%). There were 14 patients (60.8%) with glomerular filtration rate (GFR) below 60 ml/ min, who were considered acute renal failure. One patient needed plasma treatment, 2 needed hemodialysis. Mortality rate was 26%. Conclusion: COVİD-19 infection causes kidney failure in patients with kidney transplant. Mortality is high in kidney transplant patients with COVİD-19 infection. Suggested poor prognostic factors increasing death risk are being 60 years or older, recent transplantation, low oxygen saturation level, high WBC count, high CRP level, high troponin level, high D-dimer level, high creatinine level, low GFR value, low sodium level.