Clinical Characteristics, Surgical Management, and Outcomes of Appendiceal Neoplasms: Retrospective Study of 35 Cases Apendiks Neoplazmlarının Klinik Özellikleri, Cerrahi Yönetimi ve Sonuçları: 35 Olgunun Retrospektif İncelemesi
Turkiye Klinikleri Journal of Medical Sciences, cilt.45, sa.3, ss.141-147, 2025 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 45 Sayı: 3
- Basım Tarihi: 2025
- Doi Numarası: 10.5336/medsci.2024-107563
- Dergi Adı: Turkiye Klinikleri Journal of Medical Sciences
- Derginin Tarandığı İndeksler: Scopus, Central & Eastern European Academic Source (CEEAS), CINAHL, EMBASE, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.141-147
- Anahtar Kelimeler: adenocarcinoma, appendectomy, Appendiceal neoplasms, mucinous neoplasms, neuroendocrine tumor
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Appendiceal neoplasms are rare, present di agnostic challenges due to nonspecific symptoms resembling acute ap pendicitis. This study aims to evaluate the clinical characteristics, diagnostic accuracy, surgical management, long-term outcomes of pa tients with appendiceal neoplasms who underwent appendectomy. Ma terial and Methods: A retrospective analysis was conducted on 35 patients diagnosed with appendiceal neoplasms from a cohort of 3,361 appendectomy cases at the Haydarpaşa Numune Training and Research Hospital between 2013-2023. Data on demographics, preoperative imaging, intraoperative findings, histopathological results, surgical in terventions, and follow-up outcomes were analyzed. Results: Of the 35 patients, 19 (54.3%) were female, and 16 (45.7%) were male, with a meanage of 42.7 years. The most common diagnosis was appendix neuroendocrine tumor (57.1%), followed by mucinous neoplasms and colonic-type adenocarcinomas. None of the neoplastic cases were di agnosed preoperatively. Laparoscopic appendectomy wasperformed in 14.3% of cases, with the remaining patients undergoing open surgery.Right hemicolectomy was required in 7 (20%) cases. Postoperative colonoscopy was performed for all patients, with adenocarcinoma cases enrolled in colorectal cancer follow-up programs. During the follow-up period, 2 (5.7%) patients died of advanced disease, while the remain ing patients showed good long-term survival, witha mean follow-up of 59 months. Conclusion: Although appendiceal neoplasms are rare, they present significant diagnostic and management challenges. Early de tection is difficult, but appropriate surgical management and rigorous follow-up, particularly for adenocarcinoma cases, are crucial for im proving outcomes. Advancements in imaging and molecular diagnos tics may improve preoperative detection in the future.