De Ritis ratio: How effectively can we use in bladder cancer management?
Biomarkers in Medicine, cilt.14, sa.15, ss.1453-1460, 2020 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 14 Sayı: 15
- Basım Tarihi: 2020
- Doi Numarası: 10.2217/bmm-2020-0212
- Dergi Adı: Biomarkers in Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core, EMBASE, MEDLINE
- Sayfa Sayıları: ss.1453-1460
- Anahtar Kelimeler: bladder cancer, De Ritis ratio, muscle-invasive bladder cancer, nonmuscle invasive bladder cancer, risk groups
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: This study aims to determine the relationship between the pre-operative De Ritis ratio (DRR) and bladder cancer (BCa) pathological subtypes. Results methodology: A total of 248 patients with primary BCa were included. Univariate and multivariate analyses were performed to identify whether DRR can be a risk factor for the presence of carcinoma in situ (CIS). There was a statistically significant difference between the nonmuscle invasive BCa risk groups and the muscle-invasive BCa group according to the median DRR levels (p < 0.001). DRR was an independent risk factor for the presence of CIS in multivariate analysis (OR: 1.909; 95% CI: 0.030-0.196; p = 0.008). Discussion conclusion: DRR can be considered as an independent risk factor for the presence of CIS in patients with primary BCa.