Assessment of Autonomic Nervous System in Children with Celiac Disease: A Heart Rate Variability Study


Kayali S., SELBUZ S.

Indian Pediatrics, cilt.57, sa.8, ss.719-722, 2020 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Sayı: 8
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1007/s13312-020-1915-6
  • Dergi Adı: Indian Pediatrics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.719-722
  • Anahtar Kelimeler: Complications, Comorbidity, Extra-intestinal, Neurological involvement
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Objective: We evaluated the activity of autonomic nervous system in children with celiac disease by using heart rate variability (HRV) analysis. Methods: HRV parameters of 37 children with celiac disease were compared to 36 age- and sex-matched healthy controls. None of the participants had a systemic, central or peripheral neurological disease. Results: Statistically significant differences were present in two parameters; standard deviation of all RR intervals (SDNN) and standard deviation of 5-minute RR interval means (SDANN). Age was negatively correlated with mean, minimum and maximum heart rate. Duration of disease was positively correlated with low frequency power-high frequency power ratio. No correlation was found between anti-tissue transglutaminase IgA level and HRV parameters. Conclusion: Celiac disease may affect autonomic nervous function in children even if there are no symptoms of dysautonomia.