C-Reactive Protein to Albumin Ratio: A Reliable Marker in Gastric Cancer Surgery
Indian Journal of Surgery, cilt.83, sa.1, ss.92-99, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 83 Sayı: 1
- Basım Tarihi: 2021
- Doi Numarası: 10.1007/s12262-020-02310-y
- Dergi Adı: Indian Journal of Surgery
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, Veterinary Science Database
- Sayfa Sayıları: ss.92-99
- Anahtar Kelimeler: Albumin, C-reactive protein, C-reactive protein to albumin ratio, Gastric cancer, Postoperative complications
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
We aim to evaluate the association between elevated postoperative C-reactive protein to albumin ratio (CAR) and major complications in gastric cancer patients. A retrospective review was made of 177 patients who underwent a curative resection due to gastric cancer between 2013 and 2018. The cut-off level for CAR on postoperative 3rd day was determined based on a receiver operating characteristic (ROC) curve analysis. The ROC curve analysis determined an optimal cut-off level of 5 g/dl (AUC, 0.680; p = 0.001). The rate of postoperative complications was higher in patients with a CRP value of ≥5 g/dl (61.02%) (p < 0.001). Major complications occurred in 23 patients (38.98%) with a CAR of ≥ 5 g/dl on postoperative day 3 (p < 0.001). In addition, CAR was found to be higher in patients with longer operation durations and length of hospital stay (p = 0.046 and p < 0.001, respectively). Postoperative complications can be prevented in a timely manner, morbidity rates can be reduced, and thereby, patient quality of life can be improved by determining CAR in the early period.