The prognostic role of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in patients with aspiration pneumonia Aspirasyon pnömonili hastalarda nötrofil lenfosit orani ve platelet lenfosit oraninin prognoz ile ilişkisi
Turk Geriatri Dergisi, cilt.22, sa.4, ss.400-408, 2019 (SCI-Expanded, SSCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 22 Sayı: 4
- Basım Tarihi: 2019
- Doi Numarası: 10.31086/tjgeri.2020.118
- Dergi Adı: Turk Geriatri Dergisi
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.400-408
- Anahtar Kelimeler: Aspiration pneumonia, Neutrophil, Lymphocyte, Platelet, Mortality, Intensive care unit
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Introduction: Aspiration pneumonia is difficult to diagnose, and it has a high mortality rate. In this study, the prognostic values of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) and their association with intensive care unit (ICU) admission and mortality were investigated in patients with aspiration pneumonia. Materials and Method: Between November 2016 and December 2018, 162 patients aged>40 years, with no immunosuppression or malignancy, and hospitalized with a diagnosis of aspiration pneumonia were included in this retrospective study. The patients were divided into two groups: those with and without ICU admission. In addition, the patients were divided into two groups: those who died and recovered. NLR and PLR ratios were compared between groups. Results: Among the 162 patients, 87 (54%) were male and 75 (46%) were female, 72 patients were administered to the ICU, and 28 died. NLRs in patients admitted to the ICU (13.88±10.83) compared with those who were not admitted (10.5±10.07) and NLRs in patients who died (14.91±9.41) compared with those who recovered (11.4±10.67) were significantly high (p<0.05). There was no significant difference between the groups for PLRs (p>0.05). The NLR cutoff value was determined as 8, and sensitivity and specificity for admission to the ICU was 68.25% and 58.89%, respectively (AUC, 0.62), whereas sensitivity and specificity for mortality were 67.86% and 54.48%, respectively (AUC, 0.658). Conclusion: NLR has a prognostic value in predicting ICU admission and mortality in patients with aspiration pneumonia.