Albendazole-induced anagen effluvium: A brief literature review and our own experience


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Turan Ç., Metin N.

Acta Dermatovenerologica Alpina, Pannonica et Adriatica, cilt.29, sa.3, ss.161-163, 2020 (ESCI, Scopus)

Özet

Albendazole is a drug commonly used for treating many parasitoses. The primary mechanism of action is inhibition of microtu-bule polymerization binding to β-tubulin, similar to colchicine as a microtubule formation inhibitor. It is reasonable that these two antimitotic drugs can cause side effects such as alopecia and cytopenia by a similar mechanism. In the literature, only one albendazole-induced anagen effluvium has been reported. This article presents two cases of anagen effluvium that developed 2 weeks after oral albendazole administration, summarizes all cases reported to date, and offers recommendations for a diagnostic approach.