Neuroborreliosis Noroborreliosis
SENDROM, cilt.12, sa.5, ss.109-115, 2000 (Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 12 Sayı: 5
- Basım Tarihi: 2000
- Dergi Adı: SENDROM
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.109-115
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Lyme disease is an infection caused by the spirochete Borrelia burgdorferi, which is transmitted by Ixodes ticks. Neuroborreliosis is an infection of nervous system caused by this spirochete. The clinical course of Lyme disease is variable, and is divided into a localized and disseminated stages. It usually begins with a characteristic skin lesion, erythema migrans, several days after a tick bite. Neurological, cardiac, chronic skin, or articular involvement develops later. Central and peripheral nervous system disturbances can appear at any time within the disseminated. It has been estimated that 10 to 40 % of patients with Lyme disease have neurological signs and symptoms. The diagnosis of Lyme disease is based on recognizing the characteristic clinical presentations. Primary and secondary erythema migrans, Borrelia lymphocytoma, and acrodermatitis chronica atrophicans are characteristic dermatologic lesions that establish the diagnosis of Lyme disease. Serologic testing is an adjunct to clinical diagnosis. Lyme disease usually responds to antibiotic therapy. Borrelia burgdorferi is sensitive to the amoxicillin, doxycycline, ceftriaxone, cefotaxime, penicillin G, erythromycin, chloramphenicol and tetracyline. During localized infection stage and patients with facial paralysis oral antibiotic treatment is sufficient and during disseminated infection stage besides neurological deficiencies other than facial paralysis should be treated with parentheral antibiotics.